Alveolar flooding at high altitude: failure of reabsorption?

نویسندگان

  • Sabine Höschele
  • Heimo Mairbäurl
چکیده

Na-driven fluid reabsorption prevents alveolar fluid accumulation. Hypoxia augments fluid filtration by hemodynamic effects and inhibits Na reabsorption in cultured cells. A combination of both effects in vivo causes alveolar flooding, edema, thickening of the diffusion barrier for oxygen, and hypoxemia, a life-threatening situation for mountaineers in remote high-altitude mountain ranges.

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عنوان ژورنال:
  • News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society

دوره 18  شماره 

صفحات  -

تاریخ انتشار 2003